… Some acridine and acridone derivatives with anticancer activity are reported to be effective
… action of cytotoxic and antitumor 1-nitroacridines. III. In vivo interstrand cross-linking of DNA …

… Additionally, their anticancer activity was enhanced when bound to quaternary quantum dots…
action of cytotoxic and antitumor 1-nitroacridines. III. In vivo interstrand cross-linking of DNA …

… According to our knowledge, the anticancer activity of these compounds has not … Cytotoxic
and antitumor activity of 1-nitroacridines as an after effect of their interstrand DNA cross-linking …

… of its mechanism of action include: the inhibition of DNA … The specific feature of antitumor
9-amino-1-nitroacridines (… of the substrate antitumor activity. Metabolite M4′ maintained partial …

… intrastrand crosslinks in reactions with DNA, however, the scientific consensus is that ICLs
are the major cytotoxic … cell lines, our results suggest that the cytotoxicity of mitomycins toward …

… -1-nitroacridines were also developed as antitumor … therapeutic efficacy and the adverse
side effects, both resulting from … in our laboratory, expressed significantly higher cytotoxicity …

… the active tyrosine further from the DNA and thus reduce its ability to cleave DNA. P437L
mutation played a crucial role in deciphering the mechanism involved in ATP-dependent …

… the active tyrosine further from the DNA and thus reduce its ability to cleave DNA. P437L
mutation played a crucial role in deciphering the mechanism involved in ATP-dependent …

… antitumor DNA-binding agents, this class of acridine derivatives plays an important role both
in the number of active compounds and in the importance of DNA … of our knowledge, there is …